A man with a rare cancer-causing genetic mutation has fathered at least 67 children through sperm donation, with 10 diagnosed with cancer so far. This alarming case has reignited discussions on the necessity for international regulations on sperm donation limits. Experts, including Dr. Edwige Kasper, are advocating for a cap on the number of children a single donor can father in order to mitigate the risks of widespread genetic disease dissemination and improve tracking of affected families. The study reveals complications caused by the lack of screening measures capable of identifying specific genetic variants at the time of sperm donation.
The case emphasizes the necessity for a European limit on the number of births per sperm donor due to rising concerns about genetic diseases.
Dr. Kasper's investigation concluded that the mutation could likely cause Li-Fraumeni syndrome, a severe inherited cancer predisposition.
Experts worry about the social and psychological implications of having large numbers of children from a single sperm donor across various countries.
The issue of tracking families affected by genetic diseases becomes increasingly complex when a single donor contributes to many children.
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