
"The New York Jets and the Buffalo Bills play the last regular season game at Highmark Stadium in Orchard Park, New York. Buffalo could choose to rest starters after the 13-12 loss to the Philadelphia Eagles in Week 17 handed the AFC East title to New England. It seemed like the Jets were headed for the first overall pick with a seven-game losing streak to start the season, including a 30-10 loss to Buffalo at MetLife Stadium in Week 2."
"Aaron Glenn's club played well in late October and early November, but injuries forced the head coach to turn to undrafted rookie Brady Cook to finish the 2025 campaign. Despite a pending postseason appearance, Buffalo is not in a position to receive a home playoff contest. Therefore Sunday's matchup will likely serve as the farewell song to the Bills home since 1973. As the 6th seed in the AFC playoffs entering Week 18, Buffalo would need a miracle to bring the postseason back to Highmark Stadium."
"NFL Week 18 Odds: Jets at Bills Spread BUF -7 Moneyline NYJ +270, BUF +335 Over-Under Total 38.5 points Money Against the Spread 74% BUF Bets Against the Spread 86% BUF Odds via FanDuel Sportsbook Odds are subject to change Buffalo is listed as an overwhelming favorite with a 91% chance of victory on Sunday afternoon, per ESPN."
The New York Jets visit the Buffalo Bills in Week 18 at Highmark Stadium for the venue's final regular season game. Buffalo may rest starters after a 13-12 loss in Week 17 handed the AFC East to New England, while the Bills enter as the 6th seed and face long odds to host a playoff game. The Jets endured a seven-game losing streak early and were forced to finish the season with undrafted rookie Brady Cook due to injuries. Betting lines strongly favor Buffalo, and the listed best bet emphasizes Jets rushing yards.
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