Resetting the fight-or-flight response
Briefly

A study by Penn State researchers has uncovered the molecular cycle that resets the stress response in our bodies, crucial for adapting to new stressors. The findings, published in the Journal of the American Chemical Society, detail how hormones like adrenaline and glucagon activate Protein Kinase A (PKA), a key regulator of various cellular processes. Understanding this cycle provides insights not only into stress and starvation responses but also the effects of substances like caffeine on our biochemistry.
The study highlights the importance of understanding the molecular cycle that activates PKA, a protein regulating numerous cellular functions, crucial for stress responses.
Ganesh Anand explains that hormones released during stress or starvation trigger a cycle that activates PKA, which regulates over a hundred different target proteins.
Read at ScienceDaily
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