
"Midlife is a sensitive biological window where the body becomes more susceptible to age-related stressors, which may explain why this group responds more strongly to chemical exposure. We suspect that men may be at higher risk because the aging markers we analysed are heavily influenced by lifestyle factors such as smoking, which can compound the damaging effects of these pollutants."
"Having a higher biological age can have implications for health and life expectancy as it signifies your cells are deteriorating quicker than they should be - which is linked to chronic diseases such as cancer and dementia."
"Per- and polyfluoroalkyl substances (PFAS) are a class of synthetic chemicals often used in plastics, cleaning products and non-stick coatings. They can take over 1,000 years to break down and have been detected in nearly all environments including remote Arctic areas, deep oceans, drinking water and human blood."
Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals used in plastics, cleaning products, and non-stick coatings that persist in the environment for over 1,000 years. A study of 326 older adults found that PFAS exposure accelerates biological aging, particularly in men aged 50-64. Researchers measured 11 types of PFAS in blood samples and used epigenetic clocks to estimate biological age. Two PFAS types were detected in 95% of participants. Higher PFAS concentrations, including PFNA, correlated with faster biological aging. Accelerated biological age indicates cellular deterioration linked to chronic diseases like cancer and dementia. Midlife represents a sensitive biological window where bodies become more susceptible to age-related stressors, potentially explaining why this demographic responds more strongly to chemical exposure.
#pfas-forever-chemicals #biological-aging #middle-aged-men-health #environmental-toxins #epigenetic-aging
Read at Mail Online
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