The Cleveland Guardians released their 2026 season schedule on Aug. 26. The home opener is slated for April 3 against the Chicago Cubs, with the season beginning earlier with a seven-game road trip: four games at the Seattle Mariners followed by three at the Los Angeles Dodgers. Progressive Field hosts a holiday series July 2-5 versus the Chicago White Sox and multiple summer series against National League opponents. The Guardians face eight National League interleague opponents across the season. The team has a balanced March/April home-road split (16/16), a 10-game homestand June 26-July 5, and a nine-game road trip June 16-24.
That makes it a perfect time to actually look forward to next year. The team released its 2026 season schedule Tuesday, Aug. 26. The most notable date for Guardians fans look forward to? The unofficial national holiday of the home opener, which is slated for April 3 when they will open the home schedule with the Chicago Cubs, the second time they've played an opener against a National League team.
How many times will the Cleveland Guardians face National League teams in MLB interleague play? The Guardians will play eight interleague opponents including the Chicago Cubs (April 3-5), Cincinnati Reds (May 15-17), Washington Nationals (May 25-27), Pittsburgh Pirates (July 17-19), Arizona Diamondbacks (July 31-Aug, 2), New York Mets (Aug. 4-6), San Diego Padres (Aug. 14-16) and San Francisco Giants (Aug. 18-20), according to a release.
The Guardians home and road game ratio are as follows: March/April: (16 home/16 road) The Guardians have one 10-game homestand, the longest of the season from June 26-July 5 when they will play Seattle, Texas and Chicago White Sox. Their longest road trip lasts nine games from June 16-24 when they will travel to Milwaukee, Houston and Chicago to face the White Sox.
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