The APOE ε4 gene variant increases the risk of Alzheimer's disease and other age-related brain disorders like Parkinson's and motor neuron disease. Researchers utilized a new proteomics database to examine the proteins associated with this gene variant, linking them to chronic inflammation. The study suggests that environmental factors may determine whether individuals with the APOE ε4 variant develop specific degenerative conditions. Meanwhile, the NIH plans to disinvite several scientists from advisory positions, resulting in potential understaffing, and there are concerns about the manipulation of open-access health databases leading to low-quality research output.
A gene variant known as APOE ε4 increases the risk of Alzheimer's disease and vulnerability to other age-related brain disorders such as Parkinson's disease and motor neuron disease.
Environmental factors potentially influence whether individuals with the APOE ε4 variant will develop specific degenerative brain conditions, according to study co-author Caitlin Finney.
The NIH is set to disinvite many scientists from advisory councils responsible for grant applications, creating potential understaffing issues and allowing for politically influenced replacements.
Open-access health databases are reportedly being exploited to produce a significant number of low-quality, formulaic research papers.
Collection
[
|
...
]