
"It's cool to show that CRISPR works and you can create CRISPR-altered horses,"
"Horse[riders] often feel very strongly about breeding as an art and not a science, but really it is both together,"
Five cloned horses were created with CRISPR-Cas9 edits to the myostatin gene intended to accelerate muscle development and improve speed. Researchers edited fetal fibroblasts to produce embryos via cloning, then implanted the embryos into mares. The animals were developed by Kheiron Biotech in Buenos Aires about ten months ago. The edits have provoked concern among Argentine polo breeders about livelihoods and the integrity of selective breeding, prompting the Argentine Polo Association to ban gene-edited horses. Some scientists view the project as proof that CRISPR can alter horses, and gene-edited animals are increasingly moving toward commercial agricultural uses.
Read at Nature
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