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Medicine
fromNature
2 days ago

CRISPR vs. cholesterol: can gene editing prevent heart disease?

CRISPR-Cas9 disabling ANGPTL3 reduced LDL cholesterol and triglycerides by about 50% at the highest dose, indicating potential for a one-time cardiovascular-risk therapy.
fromWIRED
6 days ago

A Gene Editing Therapy Cut Cholesterol Levels by Half

In a step toward the wider use of gene editing, a treatment that uses Crispr successfully slashed high cholesterol levels in a small number of people. In a trial conducted by Swiss biotech company Crispr Therapeutics, 15 participants received a one-time infusion meant to switch off a gene in the liver called ANGPTL3. Though rare, some people are born with a mutation in this gene that protects against heart disease with no apparent adverse consequences.
Medicine
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