#clonal-hematopoiesis

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Medicine
fromNews Center
1 month ago

How Inflammation Fuels Blood Cancer Risk - News Center

TP53-mutant hematopoietic stem cells gain advantage under chronic inflammation via NLRP1 inflammasome activation and altered RNA processing, driving clonal expansion and leukemia risk.
fromwww.nature.com
10 months ago
Cancer

Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis

Somatic DNMT3A R882 mutations are key drivers of clonal hematopoiesis associated with hematologic disorders.
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