Medicine
fromSFGATE
1 hour agoAfter 'unprecedented' results, SF researchers get closer to HIV cure
Electroporation is a painful procedure used in a UCSF trial to retrain the immune system against HIV.
The research team, a mixture of people from a biotech company and academic labs, used a commercial injection setup that mixes the injection of the DNA with short pulses of electricity. The electricity disrupts the cell membrane, allowing the plasmid DNA to make it inside cells. Based on animal testing, doing this in muscle cells is enough to turn the muscles into factories producing lots of broadly neutralizing antibodies.