#immune-escape

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Medicine
fromwww.nature.com
22 hours ago

Polyclonal selection of immune checkpoint mutations in thyroid autoimmunity

Somatic mutations in immune-regulatory genes may allow self-reactive lymphocytes to bypass tolerance checkpoints, contributing to autoimmune disease.
History
fromWorld History Encyclopedia
5 days ago

From smallpox to COVID: Vaccines that changed history.

Vaccination transformed public health by providing immunity against infectious diseases, significantly reducing mortality rates and eradicating smallpox.
fromwww.scientificamerican.com
5 days ago

How the wildlife trade boosts the chance of a disease jumping from animals to humans

A new study published today in Science reveals a close correlation between species in the wildlife trade and animals that are known to have passed pathogens on to humans. There's a strong link, says Jerome Gippet, an ecologist at the University of Fribourg in Switzerland.
Coronavirus
OMG science
fromNature
1 week ago

'Treasure trove' of antiviral proteins could inspire powerful molecular tools

Bacteria possess a vast array of antiviral proteins, identified through machine-learning algorithms, which could lead to innovative biotechnologies.
Cancer
fromNature
1 week ago

Why some cancer-fighting immune cells lose their strength inside tumours

Mitochondrial health in dendritic cells is crucial for effective immune response against tumors, potentially enhancing cancer immunotherapy effectiveness.
#covid-19
Coronavirus
fromBoston.com
2 weeks ago

What to know about the highly mutated new COVID strain found in Mass. wastewater

BA.3.2, a new COVID-19 variant, is spreading globally and may evade immunity from current vaccines, raising concerns about its potential impact in the U.S.
Coronavirus
fromSFGATE
2 weeks ago

Mutated viral variant found in US for first time in SFO traveler

A new COVID-19 variant, BA.3.2, is emerging and may evade immunity from previous infections or vaccinations.
fromwww.scientificamerican.com
2 weeks ago

Why you should keep getting mRNA vaccines

mRNA vaccines have demonstrated their ability to prevent approximately eight million COVID infections within the first six months of their rollout, showcasing their effectiveness in combating the pandemic.
Coronavirus
Public health
fromPsychology Today
1 month ago

What Should You Say to Anti-Vaxxers to Keep Us All Healthy?

Vaccine mandates appropriately prioritize public health over individual autonomy when disease transmission endangers others, similar to restricting dangerous individual freedoms.
Medicine
fromNature
1 month ago

Daily briefing: Vaccine-carrying mosquitoes could inoculate bats against rabies

Engineered mosquitoes carrying vaccines in saliva show promise for preventing rabies and Nipah virus transmission from bats to humans, though field effectiveness remains uncertain.
Public health
fromNature
1 month ago

Capturing dynamic phage-pathogen coevolution by clinical surveillance - Nature

Phage-inducible chromosomal island-like elements (PLEs) in Vibrio cholerae provide defense against ICP1 phage predation, influencing pandemic strain evolution and disease severity through dynamic phage-bacteria interactions.
Coronavirus
fromwww.bbc.com
3 weeks ago

Why this 'unprecedented' outbreak isn't another Covid

Kent experienced an unprecedented meningitis outbreak with 20 cases since the weekend, unusual because meningitis typically occurs as isolated cases and spreads slower than Covid or flu.
fromThe Atlantic
4 weeks ago

I Remember a World Without Vaccines

I am open-minded; I believe in integrative practices, and I agree that the medical establishment can be arrogant and unduly influenced by the pharmaceutical industry, which now funds so much of medical research. But I fully understand Scherer's frustration with his interminable discussions with Kennedy about scientific articles.
Coronavirus
Coronavirus
fromMail Online
4 weeks ago

Climate change is fuelling deadly disease outbreaks, study warns

Climate change-driven extreme weather events directly cause disease outbreaks, with 60% of Peru's 2023 dengue cases linked to cyclone-induced rainfall and warm temperatures.
Coronavirus
fromArs Technica
1 month ago

We study pandemics, and the resurgence of measles is a grim sign of what's coming

Measles outbreaks impose substantial economic costs through containment, medical expenses, and productivity losses, while declining vaccination coverage threatens control of multiple infectious diseases.
#universal-vaccine
fromwww.npr.org
1 month ago

Vaccinating bats could be good for people. But how do you vaccinate a bat?

Bats carry a lot of very deadly pathogens like Ebola virus, Nipah, Hendra, coronavirus, and also rabies virus. People are finding more and more bat-borne viruses. When such viruses are transmitted to humans, the results are often fatal so there's a lot of interest in trying to prevent spillover in the first place.
Coronavirus
fromNature
1 month ago

Using mosquitoes to vaccinate bats could curb the spread of deadly diseases

In a study published in Science Advances, researchers in China fed Aedes aegypti mosquitoes blood that contained either a vaccine against Nipah virus or the rabies virus. The viruses, contained in the vaccines, replicated inside the insects and reached their salivary glands, allowing them to pass on the vaccine when feeding on bats or when the bats ate the insects.
Coronavirus
#measles
Public health
fromLos Angeles Times
2 months ago

A measles resurgence has put the U.S. at risk of losing its 'elimination' status

Reduced vaccine access and weakened public messaging contributed to a 2025 measles resurgence that threatens the U.S. measles elimination status.
Public health
fromLos Angeles Times
2 months ago

A measles resurgence has put the U.S. at risk of losing its 'elimination' status

Reduced vaccine access and weakened public messaging contributed to a 2025 measles resurgence that threatens the U.S. measles elimination status.
Coronavirus
fromMail Online
1 month ago

Scientists discover clue in viruses that reveal if they were lab-made

A new study analyzing seven viral outbreaks found no unusual genetic changes in Covid or most viruses before emergence, supporting a natural zoonotic origin rather than lab creation.
Medicine
fromNature
2 months ago

The infection enigma: why some people die from typically harmless germs

Genetic mutations in immune-related genes cause inborn errors of immunity that make some people uniquely vulnerable to severe infections and immune disorders.
#measles-outbreak
fromNature
2 months ago

Daily briefing: Why 'harmless' germs can be deadly for some people

DNA variants near a gene called MSRB3 - which is important for hearing in humans - could determine whether a dog's ears are pendulous like a basset hound's or stubby like a rottweiler's. Researchers analysed the genomes of thousands of canines and found that small, single-letter changes to DNA in a region of the genome near MSRB3 could boost the gene's activity. The boost can increase the rate at which ear cells proliferate, resulting in longer ears.
Science
Medicine
fromwww.theguardian.com
2 months ago

Positive thinking could boost immune response to vaccines, say scientists

Activating the brain's reward system (ventral tegmental area) through positive expectations enhances antibody responses to vaccination in humans.
#innate-immunity
fromFuturism
1 month ago
Medicine

Stanford's New "Universal Vaccine Formula" Nasal Spray Protects Mice Against Stunning Range of Diseases

fromFuturism
1 month ago
Medicine

Stanford's New "Universal Vaccine Formula" Nasal Spray Protects Mice Against Stunning Range of Diseases

Coronavirus
fromEsquire
1 month ago

Anyone Else Worried About the New Virus That's Hitting California?

Judge KP George, a Texas Democrat-turned-Republican facing financial crime indictments, received only 8.4% of the vote in a Republican primary election, placing last among five candidates.
Public health
fromNature
2 months ago

Why is flu so bad this year? Highly mutated variant offers answers

A mutated H3N2 influenza variant is driving an early, intense global flu season and reduces similarity to vaccines, though vaccines still protect against severe illness.
Science
fromwww.nature.com
1 month ago

Host control of persistent EpsteinBarr virus infection

Host non-genetic factors (HIV, immunosuppression, smoking) and genetic variation at MHC/HLA strongly influence blood Epstein-Barr virus (EBV) load during persistent infection.
Science
fromMail Online
2 months ago

Scientists use AI to create a virus never seen before

Scientists used AI and gene-assembly tools to create Evo-Φ2147, a novel 11-gene virus designed to kill pathogenic E. coli.
Science
fromNature
2 months ago

Daily briefing: Cancer cells stay hidden using stolen mitochondria

Cancer cells acquire immune-cell mitochondria that activate a mitochondrial pathway enabling immune evasion and lymph-node invasion.
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