The work these technicians are doing is as meticulous as that of engineers layering silicon on a microchip. Their job is to produce trial batches of perfumers' scent formulas, typically as many as 250 a day, which will be evaluated, tweaked and made again until one version is finalized.
The protein in the new study is called TRPM8, and it acts as the body's primary receptor for sensing both menthol and cold temperatures. It's a channel embedded in cell membranes that opens when triggered by dropping temperatures or cooling agents.
Dopamine is one of the most extensively studied neurotransmitters, chemicals that convey signals from cell to cell. It's the one with the highest profile outside neuroscience: often known as the 'pleasure chemical', it's depicted as the hit of reward that people get from recreational drugs or scrolling through social media. That's a gross simplification of what dopamine does; on that, researchers agree.
As we age, several things happen simultaneously in our skin. Antioxidant defenses in the skin decline, the composition of our sebum changes, and our cumulative UV exposure and environmental stress increase oxidative damage in the skin. As these things are weakening the skin, 2-nonenal has an opportunity to make its presence known.
They created an artificial 'mental map', with pleasantness along one axis and bodily reactions along the other, and charted how the brain responded while watching clips from films. The results revealed clear groupings in the way that our brains represent emotion - with guilt, anger and disgust in one corner and happiness, satisfaction and pride in the other.
I first became aware of fragrance layering while traveling in the Middle East, where it is deeply rooted in perfume culture, and after talking with people and friends from the region who shared their knowledge with me. After launching the brand, many customers started to ask me how to layer Maison Crivelli perfumes altogether, and I started to look at the different combinations which could work well.
At a time when memories are increasingly flattened into folders, feeds, and cloud backups, a new experimental device from MIT Media Lab proposes a far more intimate archive: scent. Developed by Cyrus Clarke, the Anemoia Device is a speculative yet functional prototype that translates photographs into bespoke fragrances using generative AI, inviting users not to view memories, but to inhabit them through the body.
One scientist at MIT, Cyrus Clarke, is working to do just that. Alongside a team of fellow researchers, Clarke has developed a physical machine called the Anemoia Device, which uses a generative AI model to analyze an archival photograph, describe it in a short sentence, and, following the user's own inputs, convert that description into a unique fragrance. The word "anemoia" was coined by author John Koenig and included in his 2021 book, The Dictionary of Obscure Sorrows.
Being an incense obsessive myself, it's important to note that while there's a loose parallel with the sticks you light at home, incense colognes are far more malleable and dimensional. On the skin, incense becomes an atmosphere built from resins and woods that shifts and evolves with your chemistry as it diffuses throughout the day.
Attention is the brain's filtering mechanism; what passes through that filter is what gets encoded. What gets encoded becomes memory. And memory is the raw material of identity. So in the architecture of your identity, attention is the doorway.
According to the Free Energy Principle (FEP), developed by theoretical neuroscientist Karl Friston and colleagues, much of what the brain does can be understood as minimizing such mismatches—a technical form of 'surprise' defined as the improbability of sensory input given an internal model. The proposal brings perception, action, learning, and decision-making under a single framework.
Wooden spoons as microphones, siblings spinning in socks across the floor, a mother laughing as Whitney Houston's "I Wanna Dance With Somebody" fills the room for the third time in a row-this is love. Long before children understand romance, they learn connection this way, through synchronized movement, shared joy, and the safety of familiar songs. Research on rhythm and social bonding suggests that moving in time together can regulate the nervous system and strengthen feelings of connection.
To view this video, please enable JavaScript and consider upgrading to a web browser that supports HTML5 video Media Summit and Experiential Marketing | Nov 8, 2022 Raja Rajamannar, Chief Marketing Officer of Mastercard (US), explores how the world of marketing is embracing more sensory and experiential approaches. And looks at what all marketers can learn from this broader approach.
Unlike sight or sound, smell has a direct pathway to the amygdala and hippocampus-the regions involved in emotion and autobiographical memory. Because of this connection, memories triggered by scent are often more vivid and emotionally intense than those triggered by sight.
The human brain is engineered to ignore most of what it sees and hears, according to the neuroscientists I interviewed for the audio original Viral Voices. If that's the case, how are you supposed to make a memorable impression? The empowering news is that if you understand how the brain works, what it discards, and what it pays attention to, you'll be far more persuasive than you've ever imagined. Persuasive people have influence in their personal and professional lives.
This story is about complexity, advanced math, cognition, and machine computation. But hold on. For this exercise, my task is to take this complex idea and reduce it-to simplify it into something less daunting and (I hope) a bit easier to understand. So, let's take a step back. My bet is that most of us learned our first piece of geometry with two letters: x and y.
Real estate with ocean views, stunning mountain vistas, and wide-open green spaces sell at premium prices because humans find those settings pleasing [1-5]. Certain color combinations in fashion-such as brown and forest green-blend harmoniously, while others, such as hot pink and orange, clash. And our eyes like certain proportions in visual objects (like buildings and human faces) but not others.
Neuroscientists have a name for the brain network that fires up when you're not focused on an external task: the default mode network, or DMN. It's the constellation of regions - the medial prefrontal cortex, posterior cingulate cortex, and angular gyrus among them - that hums to life when you daydream, reflect on yourself, or think about other people's mental states.
Did someone with spatial-sequence synaesthesia design the calendar app on mobile phones? Because that's how time and dates look in my brain. If you say a date to me, that day appears in a grid diagram in my head, and it shows if that box is already imprinted with a holiday, event or someone's birthday. Public holidays and special events like Christmas and Easter are already imprinted for the year, and the diagram goes backwards to about 100,000BC
I remember the first time I remembered a smell. This was remembering to the extent that it stopped me in my tracks, taking me back to a specific moment, a specific place and a specific feeling. The smell was that of a bike shop. Mainly rubber, with notes of oil and plastic and a strong hint of sheer excitement. In that instant I was about 10 years old, in Bache Brothers Cycles at Lye Cross, near Stourbridge, in the West Midlands.
There are lots of reasons why relationships fall apart; all kinds of incompatibilities can doom romance. Some are trivial, but occasionally there might be something more profound at the root of an estrangement. Recently, the concept of the "frontal lobe breakup" appeared in popular culture. The idea is that the final stage of development in the executive regions of the brain-the frontal lobes-changes someone's perspective about their relationship. The onset of advanced cognitive skills in one partner creates a gap in maturity too big to bridge.
Systematic developmental and neuro-phenomenological research is needed to understand childhood consciousness. Anyone who has spent time with young children knows they have a way of saying things that make you pause and reconsider what you thought you understood. Many report non-ordinary experiences-moments of "just knowing," feeling outside their bodies, or sensing a deep unity with the world around them. These accounts suggest a form of consciousness that is relational, pre-linguistic, and not yet organized around a solid, separate self.
