A groundbreaking study has seen the first transplantation of sperm-producing stem cells in a childhood cancer survivor. Jaiwen Hsu, who underwent chemotherapy for bone cancer at age 11, is now 26 and is testing whether reimplanting his previously frozen testicular cells can restore his fertility. With advancements in medical research at the University of Pittsburgh Medical Center, significant strides are being made to help the 85% of children surviving cancer, many of whom are at risk of infertility due to treatments. This innovative approach offers hope for many young survivors.
Jaiwen Hsu, now 26, is the first to return as an adult and test if reimplanting frozen testicular stem cells from his childhood might restore his fertility.
85% of children with cancer now survive to adulthood, but about 1 in 3 are left infertile from chemotherapy or radiation treatments.
Researchers at the University of Pittsburgh Medical Center are exploring how testicular stem cell transplants could restore fertility in boys affected by cancer.
With funding from the NIH, Pitt reproductive scientist Kyle Orwig has been investigating ways to preserve and utilize testicular cells for restoring fertility.
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