The draw for the round of 16 of the UEFA Europa League took place on February 21, determining matchups for clubs based on their performance in earlier phases. The top eight teams progressed directly to this round, while the next 16 entered a knockout playoff, from which eight qualified for the round of 16. This season's format eliminates draws for the quarterfinals and semifinals, allowing teams to anticipate potential opponents. Match dates are scheduled for March, with a final on May 21 in Bilbao.
The clubs that finished in the top eight of the UEFA Europa League went directly through to the round of 16, with others entering a playoff.
As of this season, there is no draw for quarterfinal and semifinal fixtures; the matchups are based on final league positions.
Each club in the round of 16 plays once on a Tuesday and once on a Wednesday during the first and second legs.
Clubs from the same country can face off against each other starting from the knockout playoff round.
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