A study from Northwestern University indicates that a natural compound from beneficial gut bacteria can significantly slow vitiligo progression in mice, and may help restore pigmentation. The research, published in the Journal of Investigative Dermatology, demonstrates a 74% reduction in pigment loss in treated mice. The compound decreases harmful killer T-cells while increasing beneficial regulatory T-cells, providing a potential standalone or complementary treatment option for vitiligo, especially for those not responding to existing therapies. The findings suggest new hope for the millions affected by this emotionally and physically challenging autoimmune condition.
The results in our model were astonishing. We found that administering a microbial compound weekly to vitiligo-prone mice significantly suppressed disease progression. It made a spectacular difference in an aggressive model of the disease.
This simple microbial compound could work as a standalone therapy, or in synergy with existing treatments.
Our findings about the effectiveness of microbial therapy could give hope to patients who are not well-served by existing treatments.
The product reduced killer T-cells that attack the skin's pigment and increased protective regulatory T-cells, which are typically scarce in vitiligo patients.
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