How Cellular Aging Steals Desires and Joys
Briefly

Older adults often experience feelings of depression, lack of motivation, and a sense of emptiness, which recent research attributes to biological factors rather than purely mental responses. Cellular senescence leads to the accumulation of 'zombie cells' that release inflammatory compounds causing chronic inflammation. This biological decay affects brain functions, challenging previous assumptions that mental health issues in older adults are solely psychological. The brain's unique structures, like postrema, are sensitive to these inflammatory signals, highlighting the connection between physical health and mental well-being.
Recent findings show that bodily inflammatory processes influence brain function, indicating that mental health in older adults may stem from biological decay rather than psychological factors.
The accumulation of 'zombie cells' in the body releases inflammatory signals, disrupting cognition and contributing to depression and apathy in older adults.
Although depression in older adults is often seen as a psychological issue, it may actually originate from a silent biological decay affecting brain function.
Research suggests that the brain's unique areas, like postrema, can directly perceive inflammatory signals from the body, linking physical health and mental well-being.
Read at Psychology Today
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