The Dolphins are favored by 1 1/2 points, indicating they are seen as having a slight edge in their matchup against the 49ers.
Each offense has struggled of late, but Miami's home advantage and recent defensive performance could give them a critical edge in this closely contested game.
Despite motivational issues for both teams, the Dolphins traditionally perform well against sub-.500 teams at home, which could influence their chances this week.
With playoff hopes dwindling, the 49ers face pressure, particularly quarterback Brock Purdy, to prove his worth amid a disappointing season.
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