Stephani Sutherland's article discusses the emergence of nasal spray vaccines and emphasizes the importance of mucosal immunity. While it introduces innovative vaccine methods, it notably omits critical considerations for immunocompromised individuals, such as those who have undergone organ transplants. The transplant team alerts such patients against using FluMist, a nasal influenza vaccine, due to potential health risks from the live attenuated virus. The immune systems of these patients may not effectively handle the weakened virus, highlighting the need for further discussions and research on vaccine safety in vulnerable populations.
FluMist is made with a weakened (attenuated) flu virus... A suppressed immune system, however, may not be able to stop the weakened virus from creating a real infection.
People who have received an organ transplant usually have a suppressed immune system, so live, attenuated vaccines are not recommended for such individuals.
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