Conor Murray is missing from Munster as they strive to close the gap to unbeaten Leinster, reflecting the turbulence of a challenging year.
Leinster will be led by Ireland captain Caelan Doris, but are without RG Snyman, showing their depth despite several changes.
Munster has made seven changes to their lineup in an effort to bounce back from previous defeats and assert their presence in the URC.
Leinster's eleven changes underscore their strategy to rotate players while still aiming for victory against a determined Munster side.
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