In the scene from 'The Substance,' director Coralie Fargeat reveals the psychological impact of a miracle drug gone awry. Elisabeth Sparkle, played by Demi Moore, splits her existence between her younger self and her original aging body. As the side effects intensify, she wakes to the horrifying realization of what she sacrifices, symbolized by an aged finger. The close-ups and camera angles underscore her internal struggle, emphasizing themes of identity, fear, and the societal pressures of youth.
The idea was all those close-ups that go more and more macro on the finger is to project Elisabeth's fears and Elisabeth's thoughts about what's happening to her.
Having the shot from above on Elisabeth to film her discomfort highlights that she's now threatened, oppressed by the situation, almost in a face-off with her double.
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