Auxin, a critical phytohormone, plays a vital role in plant development across various stages. Central to auxin signalling is the TIR1/AFB receptor pathway, where auxin binding leads to the degradation of Aux/IAA repressors, enabling ARF transcriptional regulators to activate specific gene expressions. Recent breakthroughs reveal that TIR1/AFB receptors possess adenylate cyclase activity, contributing to auxin functions like root growth inhibition and gravitropism. This finding challenges long-standing assumptions about auxin signalling and showcases its complexity within plant biological processes, suggesting a need for reevaluation of existing models.
The discovery of TIR1/AFB receptors having adenylate cyclase (AC) activity marks a significant advancement in understanding auxin's function in plant signalling beyond traditional pathways.
Auxin binding to TIR1/AFB receptors stabilizes interactions with Aux/IAA repressors, leading to their degradation and allowing ARF transcriptional regulators to act, creating a complex regulatory mechanism.
Collection
[
|
...
]