The 'crazy rule-defying' genes that determine sex
Briefly

The 'crazy rule-defying' genes that determine sex
"Sex is the most profound normal difference between human individuals. The discovery, molecular biology, and evolution of sex chromosomes reveal the complexities of sex determination across vertebrates."
"In humans and most mammals, sex is determined at fertilization: if a sperm bearing an X chromosome fertilizes an egg that also contains an X, the result is typically female offspring."
"Researchers know that it is the presence of the Y, rather than the absence of an X, that constitutes the first step in determining sex, complicating the narrative of biological sex."
Sex determination in humans occurs at fertilization, where the presence of a Y chromosome typically results in male offspring, while its absence leads to female offspring. However, biological sex determination is complex, with unusual chromosome combinations like XXY or XYY resulting in male development. Exceptions exist, such as male offspring with XX chromosomes or female offspring with XY chromosomes. Research has identified specific genes on the Y chromosome that play a crucial role in sex determination and development.
Read at Nature
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