Human cells are intricate with approximately 10,000 distinct proteins performing vital functions through interactions in specific cellular locations. Researchers emphasize the importance of spatial understanding in protein functions, revealing that many proteins exist in multiple locations, defying the simple one gene, one protein, one function model. Advances in spatial proteomics driven by high-resolution imaging and advanced data analysis techniques are enabling scientists to map protein locations and interactions, offering insights into cellular biology and potential therapeutic developments.
The average human cell contains roughly 10,000 different proteins... If you want to understand how cells function, you have to work out what proteins interact with - and where.
More than half of our proteins have more than one hangout spot. Cellular processes falter when proteins show up to the wrong job site.
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