"But too much coffee can have a negative effect because it "can speed up the heart, cause increased heart rate, cause contraction of the blood vessels and increased blood pressure, and certainly if you're prone to rhythm disturbances of the heart, the caffeine at high doses can cause that," Tadwalkar said. Caffeine is considered safe until 300 to 400 milligrams, and after that, it can have a cascade of negative effects."
"When the body's fight-or-flight system is chronically activated, it can cause inflammation in the body and prolonged release of stress hormones like adrenaline. These factors together can cause physiological changes in the body, including increases in blood pressure, high cholesterol, obesity, insulin resistance and electrical rhythm disturbances, according to Tadwalkar. Chronic stress can also increase the risk of blood clotting throughout the body."
Caffeinated coffee is generally safe and protective for the heart, with research indicating two cups per day offer the greatest cardiovascular benefit. Excessive coffee intake can speed up the heart, increase heart rate, constrict blood vessels and raise blood pressure, and can provoke rhythm disturbances in susceptible individuals. Caffeine is considered safe up to 300–400 milligrams; higher doses can trigger cascading negative effects. Filtered coffee is linked to better cholesterol levels than unfiltered brew, and blacker coffee is generally healthier. Chronic unmanaged stress activates fight-or-flight responses, causing inflammation, hormonal release, metabolic changes and increased clotting risk, which elevate heart attack risk.
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