"Targeted treatments for cats with cancer might be on the horizon. Join Our Community of Science Lovers!Sign Up for Our Free Daily Newsletter No one wants to think about the death of a beloved pet. But because cancer is one of the leading causes of death for our companion animals, detecting cancer early and finding treatments is imperative. Despite that fact that almost as many cats contract cancer during their lifetime as dogs do, research"
"into cancers that affect our pets has tended to focus more on dogs than cats. A new study could help close some of that gap. Senior author Louise van der Weyden, a staff scientist at the Wellcome Sanger Institute in England, and a team of researchers sequenced the genomes of tumors from almost 500 domestic cats. Their findings, published today in Science, show that the genes that drive cancer in cats are remarkably similar to those that do so in humans."
Researchers sequenced tumor genomes from nearly 500 domestic cats across 13 tumor types, including skin, bone, soft tissue and blood. The analysis searched for mutations likely driving tumor formation and identified cancer-causing genes in cats that closely mirror those in humans. The findings indicate that knowledge of feline tumor genetic alterations can inform selection of targeted therapies and may enable development of treatments benefiting both cats and humans. The work addresses a research imbalance that favored dogs, broadens comparative oncology knowledge, and supports earlier detection and precision medicine approaches for feline cancers.
Read at www.scientificamerican.com
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