Neurons are categorized into classes based on gene expression, which informs their differentiation and functional properties. The interplay of transcriptomes, morphology, and connectivity is vital for understanding neuronal phenotypes. Studies in organisms like C. elegans and Drosophila reveal how specific gene expressions shape neuron types and wiring. In the mouse visual cortex, neurons of the same transcriptomic type can exhibit significant variability in function and morphology. This underscores the need to explore external factors influencing neuron characteristics and their interaction with genetic expression.
Neurons can be classified into types based on gene expression influences, highlighting the complexity of how transcriptomes relate to a neuron's morphology and function.
The interplay among a neuron's transcriptome, developmental history, and external topology is crucial in determining its distinctive phenotype and functional capabilities.
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