#genotoxicity

#genotoxicity

DNA damage can originate from internal sources like metabolic by-products or normal cellular activities, as well as external factors such as cosmic radiation, diet, and pollution.

Plasticizers are a general term for a whole range of chemicals added to materials, typically plastic and rubber, to make them softer and more pliable. They're found in countless everyday items like plastic shower curtains, shrink-wrap, PVC raincoats or flexible tubing and wire insulation for homes. Plasticizers, sometimes called phthalates, are also found in cosmetics, like nail polishes, lotions and shampoos.

Glyphosate is one of the most commonly used methods of handling weeds on farms and elsewhere. It is a key part of modern agriculture, to the point that imagining a food system that operates without it is incredibly challenging. Yet, glyphosate is also the subject of much debate.

Glyphosate is an amino acid inhibitor, which means it stops weeds from growing by blocking their ability to produce amino acids, which are the building blocks of proteins. The herbicide is commonly applied to crops, such as corn and soybeans, that have been genetically engineered to be immune to glyphosate's deadly effects.

Exposure to a fungicide induced changes to gene expression in rats that persisted for at least 20 generations. It also increased the chance of offspring developing kidney disease, obesity or experiencing complications when giving birth, according to the longest-running study of 'epigenetic' changes in mammals.

Martschenko's argument is largely that genetic research and data have almost always been used thus far as a justification to further entrench extant social inequalities. But we know the solutions to many of the injustices in our world-trying to lift people out of poverty, for example-and we certainly don't need more genetic research to implement them. Trejo's point is largely that more information is generally better than less.

New analysis has identified 25 chemicals linked to cancer that the Food and Drug Administration ( FDA) still allows in American food production. The findings come from scientists at the Environmental Defense Fund (EDF), a nonprofit environmental advocacy group, who determined that eight of the chemicals are classified as known human carcinogens and 17 are reasonably anticipated to be human carcinogens.

Our study suggests that living near a [nuclear power plant] may carry a measurable cancer risk - one that lessens with distance. We recommend that more studies be done that address the issue of NPPs and health impacts, particularly at a time when nuclear power is being promoted as a clean solution to climate change.

The UK announced Tuesday to tackle PFAS pollution, introducing an action plan to "understand where these chemicals are coming from, how they spread and how to reduce public and environmental exposure." The plan includes monitoring of rivers, lakes and seas, supporting a transition away from PFAS and consulting on a limit for drinking water. While some have called the plan "encouraging", others have said it doesn't go far enough.

The conventional approach to evaluating the impact of air pollution is to focus on a single exposure during a fixed period of time. But evidence suggests that contaminants work together, magnifying the damage to people's lungs. Conventional studies fail to probe synergistic effects. They also ignore the cumulative effects of lifelong exposures to pollutants, known as the exposome. Researchers need to shift away from single-pollutant studies and towards those involving a broad range of exposures.