#proteomics
#proteomics

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Proteotoxic stress response drives T cell exhaustion and immune evasion - Nature

Proteomic profiling of exhausted T cells reveals pathway-specific transcript–protein discordance and identifies T cell–exhaustion-specific protein-level regulatory mechanisms.

Medicine

fromNature

1 week ago

SPP1 is required for maintaining mesenchymal cell fate in pancreatic cancer - Nature

SPP1 plasma levels increase in late-stage pancreatic ductal adenocarcinoma and in KPCY mouse models, correlating with mesenchymal marker analyses and organoid-based tumor assays.

Science

fromNature

2 months ago

One potent gene raises risk of Alzheimer's, Parkinson's and other brain diseases

APOE ε4 increases vulnerability to various neurodegenerative diseases, including Alzheimer's, Parkinson's, and motor neuron diseases.

OMG science

fromBusiness Insider

3 months ago

Forget 'biological age' tests - longevity experts are using an $800 under-the-radar blood test to measure aging in real-time

A forthcoming blood test could help tailor health decisions based on unique biology.

The organ age test (proteomics) may be a better biological age marker for assessing health.

fromNews Center

5 months ago

Novel Approach Improves Protein Characterization in Human Tissue - News Center

This technology can give you a global picture of the proteins included in one specific cell or tissue region as small as possible that can be laser captured and microdissected. This technology can be broadly applied to analyzing any cell in any tissue in a spatially-preserved manner.