Drug-induced weight gain poses significant challenges for patients with severe mental illnesses, particularly those on antipsychotics and certain antidepressants, leading to potential treatment discontinuation. Initial treatments often result in weight increases averaging 10-14 percent within the first six months. This issue can discourage patients from maintaining their medication regime despite therapeutic benefits. The effect of these medications varies widely, and both short- and long-term usage can contribute to considerable weight gain, further complicating treatment strategies. Adjustments in lifestyle, medication type, or the use of weight loss medications may alleviate some drawbacks.
Drug-induced weight gain is prevalent among patients with severe mental illnesses, particularly those on antipsychotics and antidepressants, leading to treatment discontinuation.
Long-term treatments for major depressive disorder often result in weight gain, particularly with serotonin reuptake inhibitors, which may deter patients from ongoing medication.
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