RNA molecules exhibit extensive conformational diversity that is crucial for their functions, influencing splicing, packaging, and overall cellular processes, as shown through various advanced experimental techniques.
Methods for studying RNA dynamics reveal a complex conformational landscape that traditional models fail to capture, highlighting the need for explicit 3D structural formation in RNA research.
Ribonuclease P stands out as a universal RNA enzyme across life forms, illustrating adaptability through its varying substrate recognition, underlining the importance of RNA conformational dynamics in functional versatility.
Understanding the correlation between RNA sequence conservation and conformational dynamics may enable the discovery of druggable sites, providing insights into RNA interactions with other biological macromolecules.
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