A study of over 50,000 brain scans demonstrates that features such as the thickness of the cerebral cortex and grey matter volume can indicate the rate of aging. These measurements predict cognitive decline, frailty, and disease risk. Current results are not yet ready for clinical assessment but offer advantages over blood-based aging metrics. Imaging presents direct insights that cannot be captured by molecular biomarkers. Understanding individual aging rates could help identify risks of age-related illnesses and enhance treatment assessments.
Imaging offers unique, direct insights into the brain's structural ageing, providing information that blood-based or molecular biomarkers alone can't capture.
Pivotal features include the thickness of the cerebral cortex and the volume of grey matter that the cerebral cortex contains.
Such ageing clocks could assess an individual's risk of age-related illness early in life, when it might still be possible to intervene.
Researchers have been racing to develop new measures that can fill the gap between chronological age and the pace of bodily aging.
Collection
[
|
...
]