Alzheimer's disease was first recorded in 1906 with Auguste Deter, revealing critical symptoms and brain changes associated with the disease. While the understanding of Alzheimer’s has improved over time, women remain disproportionately affected, comprising two-thirds of those diagnosed. Women not only have a higher risk but are also often diagnosed later and experience faster cognitive decline. This gender disparity has largely been neglected, but recent research is focusing on gender differences to better understand Alzheimer's pathology and develop effective interventions.
"We owe women a century of research," says Lisa Mosconi, highlighting the historical oversight in studying Alzheimer's disease specifically in female patients, despite their higher prevalence.
"We still have far to go and more to do," says Dena Dubal, emphasizing the ongoing need for research into how gender influences Alzheimer's pathology and progression.
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