#cellular-oxygen-sensing tag

That minty fresh feeling? Scientists now know how our bodies feel cold

TRPM8 is the primary receptor for sensing menthol and cold temperatures, crucial for understanding cold hypersensitivity therapies.

Medicine

fromenglish.elpais.com

A newly-discovered molecular process explains how our bodies perceive the cold

Research on the TRPM8 protein reveals its role in cold sensation, potentially leading to new treatments for cold-induced pain.

OMG science

That minty fresh feeling? Scientists now know how our bodies feel cold

TRPM8 is the primary receptor for sensing menthol and cold temperatures, crucial for understanding cold hypersensitivity therapies.

Medicine

fromenglish.elpais.com

A newly-discovered molecular process explains how our bodies perceive the cold

Research on the TRPM8 protein reveals its role in cold sensation, potentially leading to new treatments for cold-induced pain.

Scientists discover a hidden system that turns brown fat into a calorie burner

A newly identified protein system enhances brown fat's ability to burn calories, potentially leading to obesity treatments that boost metabolism.

Science

fromNature

Synthetic circuits for cell ratio control - Nature

Synthetic biology enables artificial cell differentiation and division of labor by engineering genetic and epigenetic circuits that mimic natural stem cell asymmetric division processes.

Medicine

fromFast Company

Experts say this activity rebuilds mitochondria and may slow aging

Mitochondrial dysfunction emerges as a key factor in aging-related diseases like Alzheimer's and cancer, as these organelles deteriorate and produce toxic byproducts over time.

Health

fromScienceDaily

Scientists discover diet that tricks the body into burning fat without exercise

Reducing methionine and cysteine amino acids in diet triggers thermogenesis in mice, causing significant weight loss comparable to constant cold exposure without requiring increased exercise or reduced food intake.

fromwww.nature.com

2 months ago

Author Correction: Nutrient-sensing nuclear receptors coordinate autophagy

In the originally published version of this article, Extended Data Fig. 4 contained inadvertent duplications introduced during figure assembly: panel 4c (the bottom of the second column) erroneously reused images from panel 4a (the bottom of the third column); panel 4c (the upper panel of the third column) erroneously reused images from panel 4a (the upper panel of the rightmost column);

Science

Health

fromInsideHook

7 Daily Habits That Can Slow Your Cellular Aging

Protecting cellular function—especially mitochondrial health and reducing senescent cell buildup—significantly improves chances of a longer, healthier life.

Science

fromNature

3 months ago

Daily briefing: Cancer cells stay hidden using stolen mitochondria

Cancer cells acquire immune-cell mitochondria that activate a mitochondrial pathway enabling immune evasion and lymph-node invasion.

fromwww.nature.com

Lipid metabolism drives dietary effects on T cell ferroptosis and immunity

Ferroptosis, a major mechanism of non-apoptotic programmed cell death, critically regulates the homeostasis and functionality of peripheral CD4+ and CD8+ T cells. Here we demonstrate that in mouse, resistance of T cells to ferroptosis depends critically on the composition of standard rodent diets, and that dietary effects on ferroptosis have a crucial role in regulation of T cell homeostasis and immune responses.

Medicine

Health

These cells in the body remember fat. Here's what that means for weight loss

Fat cells and immune cells retain epigenetic memory of obesity, making weight regain easier even after significant weight loss through any method.

Science