These 10 biotech companies are changing how we discover new drugs and treat complex diseasesBiotech companies are harnessing AI and cutting-edge research tools to enhance drug development and diagnostics.
Four rising stars at the forefront of cancer researchYoung researchers are innovating in cancer drug development, focusing on pioneering techniques like cancer reversion to reduce the need for traditional treatments.
AI has dreamt up a blizzard of new proteins. Do any of them actually work?AI-driven protein design competitions are revolutionizing the field, enabling rapid development and innovation in therapeutic proteins.
Trial of Controversial Alzheimer's Drug Halted After Disappointing ResultsCassava Sciences halted the advanced trial for simufilam as it failed to reduce cognitive decline in Alzheimer's patients, disappointing many.
These 10 biotech companies are changing how we discover new drugs and treat complex diseasesBiotech companies are harnessing AI and cutting-edge research tools to enhance drug development and diagnostics.
Four rising stars at the forefront of cancer researchYoung researchers are innovating in cancer drug development, focusing on pioneering techniques like cancer reversion to reduce the need for traditional treatments.
AI has dreamt up a blizzard of new proteins. Do any of them actually work?AI-driven protein design competitions are revolutionizing the field, enabling rapid development and innovation in therapeutic proteins.
Trial of Controversial Alzheimer's Drug Halted After Disappointing ResultsCassava Sciences halted the advanced trial for simufilam as it failed to reduce cognitive decline in Alzheimer's patients, disappointing many.
Researchers find a hint at how to delay Alzheimer's symptoms. Now they have to prove itAn experimental treatment shows promise in delaying Alzheimer's symptoms in at-risk individuals, raising concerns about funding halting patient access.
ALS Drug Effectively Treats Alzheimer's Disease in New Animal Study - News CenterNU-9 shows promise in improving neuron health across neurodegenerative diseases like ALS and Alzheimer's by targeting their common mechanisms.
Researchers find a hint at how to delay Alzheimer's symptoms. Now they have to prove itAn experimental treatment shows promise in delaying Alzheimer's symptoms in at-risk individuals, raising concerns about funding halting patient access.
ALS Drug Effectively Treats Alzheimer's Disease in New Animal Study - News CenterNU-9 shows promise in improving neuron health across neurodegenerative diseases like ALS and Alzheimer's by targeting their common mechanisms.
An Experimental Obesity Pill Mimics Gastric Bypass SurgeryThe drug developed at MIT shows promise as a weight loss treatment by enhancing nutrient absorption and regulating hunger hormones.
Daily briefing: Variant of mpox virus is getting better at human-to-human transmissionSemaglutide significantly alleviates obesity-related knee arthritis pain, matching the efficacy of painkillers.Advanced mapping of tumor cells offers crucial insights for cancer treatment development.New findings on protocell structures may shed light on the evolution of cell membranes.
An Experimental Obesity Pill Mimics Gastric Bypass SurgeryThe drug developed at MIT shows promise as a weight loss treatment by enhancing nutrient absorption and regulating hunger hormones.
Daily briefing: Variant of mpox virus is getting better at human-to-human transmissionSemaglutide significantly alleviates obesity-related knee arthritis pain, matching the efficacy of painkillers.Advanced mapping of tumor cells offers crucial insights for cancer treatment development.New findings on protocell structures may shed light on the evolution of cell membranes.
Inside the Incredible Potential of Quantum Computing in Drug Development | HackerNoonQuantum computing has the potential to significantly accelerate drug development timelines, ultimately saving lives and reducing costs.
Will AI revolutionise drug development? Researchers say it depends on how it's usedAI in drug development shows promise but requires cautious optimism and realistic expectations.Despite excitement, AI has not yet significantly improved drug success rates in clinical trials.
Pfizer Ends Development of Its Obesity PillPfizer has halted the development of danuglipron due to safety concerns, but remains committed to exploring other obesity treatment options.
Which disease-modifying Alzheimer's drugs are the most promising?The UK health watchdog has rejected two new Alzheimer's drugs due to concerns over their effectiveness and potential side effects.
PharmAbcine Announces Safety Approval for 4mg Single-dose Cohort in Phase 1 Clinical Trial of PMC-403 for Neovascular Age-related Macular DegenerationPharmAbcine is advancing monoclonal antibody therapy, significantly targeting diseases with high efficacy and low side effects.
Bay Area biotech firm once worth $13B lays off all but 15 workersAllakos announces failure of pivotal clinical trial for chronic hives drug AK006, resulting in a 75% staff layoff.
Inside the Incredible Potential of Quantum Computing in Drug Development | HackerNoonQuantum computing has the potential to significantly accelerate drug development timelines, ultimately saving lives and reducing costs.
Will AI revolutionise drug development? Researchers say it depends on how it's usedAI in drug development shows promise but requires cautious optimism and realistic expectations.Despite excitement, AI has not yet significantly improved drug success rates in clinical trials.
Pfizer Ends Development of Its Obesity PillPfizer has halted the development of danuglipron due to safety concerns, but remains committed to exploring other obesity treatment options.
Which disease-modifying Alzheimer's drugs are the most promising?The UK health watchdog has rejected two new Alzheimer's drugs due to concerns over their effectiveness and potential side effects.
PharmAbcine Announces Safety Approval for 4mg Single-dose Cohort in Phase 1 Clinical Trial of PMC-403 for Neovascular Age-related Macular DegenerationPharmAbcine is advancing monoclonal antibody therapy, significantly targeting diseases with high efficacy and low side effects.
Bay Area biotech firm once worth $13B lays off all but 15 workersAllakos announces failure of pivotal clinical trial for chronic hives drug AK006, resulting in a 75% staff layoff.
John Hartwig, chemist: The situation for science in the United States is terrible, these are the steps of authoritarian regimes to take power'John Hartwig's work in catalysis significantly impacts drug production and the economy, yet it often goes unnoticed compared to more famous scientific pursuits.
Lila Sciences Uses A.I. to Turbocharge Scientific DiscoveryA.I. is poised to transform scientific discovery by rapidly accelerating drug development, agricultural innovation, and green energy solutions.
Absci and Memorial Sloan Kettering partner to search for cancer drugs using AIArtificial intelligence in drug development shows promise through collaborations like MSK and Absci's innovative partnership.
Only an AI breakthrough can help humans live longer, argues drug developer: 'We need a ChatGPT moment in longevity'Artificial intelligence is seen as a key technology to extend human lifespan by decelerating aging and age-related diseases.
The computer that runs on human neuronsThe CL1 is the first biological computer using lab-grown neurons to advance drug development and neuroscience.
YC-backed ReactWise is applying AI to speed up drug manufacturing | TechCrunchReactWise uses AI to speed up drug manufacturing by optimizing chemical processes, significantly improving efficiency and accuracy.
Lila Sciences Uses A.I. to Turbocharge Scientific DiscoveryA.I. is poised to transform scientific discovery by rapidly accelerating drug development, agricultural innovation, and green energy solutions.
Absci and Memorial Sloan Kettering partner to search for cancer drugs using AIArtificial intelligence in drug development shows promise through collaborations like MSK and Absci's innovative partnership.
Only an AI breakthrough can help humans live longer, argues drug developer: 'We need a ChatGPT moment in longevity'Artificial intelligence is seen as a key technology to extend human lifespan by decelerating aging and age-related diseases.
The computer that runs on human neuronsThe CL1 is the first biological computer using lab-grown neurons to advance drug development and neuroscience.
YC-backed ReactWise is applying AI to speed up drug manufacturing | TechCrunchReactWise uses AI to speed up drug manufacturing by optimizing chemical processes, significantly improving efficiency and accuracy.
AI can call the shots on drug making because it 'doesn't have a career at stake,' major pharma CEO saysAI is used by Sanofi to make unbiased decisions on drug development, as it lacks personal attachments.
New drug for lower back pain could be a gamechanger'A new antibiotic drug, PP353, shows promise in treating severe back pain caused by infections, potentially changing treatment paradigms.
AI can call the shots on drug making because it 'doesn't have a career at stake,' major pharma CEO saysAI is used by Sanofi to make unbiased decisions on drug development, as it lacks personal attachments.
New drug for lower back pain could be a gamechanger'A new antibiotic drug, PP353, shows promise in treating severe back pain caused by infections, potentially changing treatment paradigms.
Generalizing arene CH alkylations by radicalradical cross-coupling - NatureDynamic orbital selection offers a novel approach to efficiently introduce diverse alkyl fragments into molecular scaffolds for drug optimization.
New schizophrenia drug could treat Alzheimer's diseaseA new era in psychiatric medicine is suggested by the approval of innovative drugs, though not all trials yield positive results.
A yoga pill' to end anxiety? Neuroscientists discover a brain circuit that instantly deflates stressA new study reveals a brain pathway that can help combat anxiety by regulating voluntary breathing, offering potential for future calming drugs.
Revolutionary drug for schizophrenia wins US approvalKarXT represents a groundbreaking schizophrenia treatment with a unique mechanism of action that may improve patient outcomes and tolerability compared to existing therapies.
Safer Psychedelic Drugs May Be ComingPsychedelics offer therapeutic potential for mental health, yet face challenges including safety concerns and regulatory hurdles that could be addressed through next-generation approaches.
Psychopharmaceuticals: 50 years of stagnation?Mental health treatments from the 1950s and 1960s largely remain unchanged, according to critique by Professor David Nutt.
Startups Are Biohacking Psychedelic Drugs to Make Sure You Never Have a Bad Trip AgainPharmaceutical companies are developing next-generation psychedelics to serve as safer psychotherapy treatments, with promising early research on compounds like R-MDMA.
New schizophrenia drug could treat Alzheimer's diseaseA new era in psychiatric medicine is suggested by the approval of innovative drugs, though not all trials yield positive results.
A yoga pill' to end anxiety? Neuroscientists discover a brain circuit that instantly deflates stressA new study reveals a brain pathway that can help combat anxiety by regulating voluntary breathing, offering potential for future calming drugs.
Revolutionary drug for schizophrenia wins US approvalKarXT represents a groundbreaking schizophrenia treatment with a unique mechanism of action that may improve patient outcomes and tolerability compared to existing therapies.
Safer Psychedelic Drugs May Be ComingPsychedelics offer therapeutic potential for mental health, yet face challenges including safety concerns and regulatory hurdles that could be addressed through next-generation approaches.
Psychopharmaceuticals: 50 years of stagnation?Mental health treatments from the 1950s and 1960s largely remain unchanged, according to critique by Professor David Nutt.
Startups Are Biohacking Psychedelic Drugs to Make Sure You Never Have a Bad Trip AgainPharmaceutical companies are developing next-generation psychedelics to serve as safer psychotherapy treatments, with promising early research on compounds like R-MDMA.
Bay Area biotech company, once worth $1.2 billion, lays off almost entire staffCargo Therapeutics is laying off nearly all its employees after ceasing drug development due to trial failures, marking a major decline for the biotech firm.
Archon emerges from stealth with $20M and 'antibody cages' to power up drug development | TechCrunchArchon Biosciences aims to revolutionize antibody treatments through innovative protein 'cages' that improve drug binding and efficacy.
Bay Area biotech company, once worth $1.2 billion, lays off almost entire staffCargo Therapeutics is laying off nearly all its employees after ceasing drug development due to trial failures, marking a major decline for the biotech firm.
Archon emerges from stealth with $20M and 'antibody cages' to power up drug development | TechCrunchArchon Biosciences aims to revolutionize antibody treatments through innovative protein 'cages' that improve drug binding and efficacy.
Many life-saving drugs fail for lack of funding. But there's a solution: desperate rich peopleLa Fondation Brocher is key in medical ethics research, influencing drug development, yet many effective drugs remain abandoned.
A Twice-Yearly Shot Prevents HIV, Study FindsTwice-yearly AIDS shots are 100% effective in preventing new infections in women.
2021: Anti-amyloid antibodies take a bumpy road to the clinicThe initial disease-modifying therapy for Alzheimer's sparked complex reactions rather than unbridled joy.
Many life-saving drugs fail for lack of funding. But there's a solution: desperate rich peopleLa Fondation Brocher is key in medical ethics research, influencing drug development, yet many effective drugs remain abandoned.
A Twice-Yearly Shot Prevents HIV, Study FindsTwice-yearly AIDS shots are 100% effective in preventing new infections in women.
2021: Anti-amyloid antibodies take a bumpy road to the clinicThe initial disease-modifying therapy for Alzheimer's sparked complex reactions rather than unbridled joy.
How pharmaceutical companies are training their workers on AIPharmaceutical companies are prioritizing upskilling through AI training to enhance productivity in drug development.
How neuroscientists are designing a safer opioidResearchers are working on creating a new drug that mimics the pain-relief effects of opioids without their addictive and deadly effects.
Pain researchers must learn from the opioid crisisA new strategy for analgesic drug development is necessary to prevent opioid addiction and find safer pain relief alternatives.
FDA OK's painkiller designed to end opioids' addiction and overdose riskJournavx offers a new pain management solution without the addiction risks of opioids.
New Pain Medication Prevents Pain from Reaching the BrainA new class of drugs may treat chronic pain effectively without the addictive properties of opioids.
How neuroscientists are designing a safer opioidResearchers are working on creating a new drug that mimics the pain-relief effects of opioids without their addictive and deadly effects.
Pain researchers must learn from the opioid crisisA new strategy for analgesic drug development is necessary to prevent opioid addiction and find safer pain relief alternatives.
FDA OK's painkiller designed to end opioids' addiction and overdose riskJournavx offers a new pain management solution without the addiction risks of opioids.
New Pain Medication Prevents Pain from Reaching the BrainA new class of drugs may treat chronic pain effectively without the addictive properties of opioids.
Genomics pioneer steps closer to dementia treatment breakthroughArctic Therapeutics pioneers drug development using genomic data, aiming to cut risks, costs, and times while addressing root causes of diseases.
The U.S. Must Lead the Global Fight against SuperbugsAntimicrobial resistance could lead to 39 million deaths by 2050; urgent U.S. government action is essential to combat this crisis.
Glox Therapeutics Awarded Share of 3M Collaborative Discovery Programme Funding from Cystic Fibrosis Antimicrobial Resistance SyndicateGlox Therapeutics is developing precision antibiotics to address antimicrobial resistance in cystic fibrosis.
The U.S. Must Lead the Global Fight against SuperbugsAntimicrobial resistance could lead to 39 million deaths by 2050; urgent U.S. government action is essential to combat this crisis.
Glox Therapeutics Awarded Share of 3M Collaborative Discovery Programme Funding from Cystic Fibrosis Antimicrobial Resistance SyndicateGlox Therapeutics is developing precision antibiotics to address antimicrobial resistance in cystic fibrosis.
Breakthrough drugs herald new era' in battle against dementia, experts predictPills preventing or mitigating Alzheimer's disease are emerging, with new drugs set to be available, promising a new era in dementia care.
Novel antibiotics: Regional research is (half) the solution DW 01/15/2025Antibiotic resistance is escalating, necessitating urgent local drug development, particularly in low- and middle-income countries.
Breakthrough drugs herald new era' in battle against dementia, experts predictPills preventing or mitigating Alzheimer's disease are emerging, with new drugs set to be available, promising a new era in dementia care.
Novel antibiotics: Regional research is (half) the solution DW 01/15/2025Antibiotic resistance is escalating, necessitating urgent local drug development, particularly in low- and middle-income countries.
Martin Karplus, who took biochemistry to cyberspace, dies at 94Martin Karplus revolutionized theoretical chemistry by merging physics and computer modeling, which advanced our understanding of biochemical reactions.
Esteemed Molecular Biologist Named Winner of 2025 Kimberly Prize - News CenterRon Evans, PhD, received the Kimberly Prize for his breakthroughs in nuclear hormone receptors, impacting drug development and improving human health.
Partners in drug discovery: how to collaborate with non-governmental organizationsBiomedical discoveries should actively seek partnerships with NGOs to bring ideas to fruition.Collaboration in scientific research can lead to rapid product development, as demonstrated during COVID-19.
Eindhoven's Chromodynamics secures 2M funding - Silicon CanalsChromodynamics raised €2M to advance its microscopy technology, aiming to revolutionize biomedical research and speed up drug development processes.
Partners in drug discovery: how to collaborate with non-governmental organizationsBiomedical discoveries should actively seek partnerships with NGOs to bring ideas to fruition.Collaboration in scientific research can lead to rapid product development, as demonstrated during COVID-19.
Eindhoven's Chromodynamics secures 2M funding - Silicon CanalsChromodynamics raised €2M to advance its microscopy technology, aiming to revolutionize biomedical research and speed up drug development processes.
Coupling of unactivated alkyl electrophiles using frustrated ion pairs - NatureEfficient construction of C-C bonds is essential in organic synthesis, with cross-electrophile coupling (XEC) reactions offering an innovative approach by avoiding organometallic reagents.
Explainer: What we know about the new 'gamechanger' anti-smoking pill and when will it arrive in Ireland?Varenicline is an anti-smoking pill introduced in the UK health service as a new solution for smoking cessation.
RFK Jr. vs. Vivek: Trump world's two paths for pharma regulationRamaswamy and Kennedy's differing views on drug regulation add uncertainty for pharmaceutical companies under the new administration.
Explainer: What we know about the new 'gamechanger' anti-smoking pill and when will it arrive in Ireland?Varenicline is an anti-smoking pill introduced in the UK health service as a new solution for smoking cessation.
RFK Jr. vs. Vivek: Trump world's two paths for pharma regulationRamaswamy and Kennedy's differing views on drug regulation add uncertainty for pharmaceutical companies under the new administration.
Eli Lilly CEO's explains how failing fast leads to successEli Lilly's CEO emphasizes the balance of technical excellence and the human impact of pharmaceuticals in combating serious health issues.
New discovery on how mutant RAS drives tumorsMutant RAS genes contribute to tumor growth through mechanisms in the nucleus, not just cell surface signaling.
Mutant-selective AKT inhibition through lysine targeting and neo-zinc chelation - NatureAKT1 E17K mutation poses a challenge for treatment; targeted inhibitors offer a promising solution without the side effect of hyperglycaemia.
Chemists make 'impossible' molecules that break 100-year-old bonding ruleChemists successfully synthesized anti-Bredt olefins, previously thought too unstable, paving the way for novel drug candidate synthesis.
Daily briefing: 'Impossible' molecules break 100-year old chemical ruleChemists have synthesized a molecule that challenges the long-standing Bredt's rule, opening new avenues in drug development.
Chemists make 'impossible' molecules that break 100-year-old bonding ruleChemists successfully synthesized anti-Bredt olefins, previously thought too unstable, paving the way for novel drug candidate synthesis.
Daily briefing: 'Impossible' molecules break 100-year old chemical ruleChemists have synthesized a molecule that challenges the long-standing Bredt's rule, opening new avenues in drug development.
Exercise in a pill: have scientists really found a drug that's as good for you as a 10km run?Mimetics like LaKe may replicate some benefits of exercise, but their true usefulness and safety remain uncertain.
Berkeley startup wins government award to develop radiation and lead poisoning treatmentHOPO Therapeutics aims to develop drugs that selectively target and remove toxic metals from the body, posing a significant health threat.
How to transform scientific discoveries into better treatmentsTransforming scientific discoveries into effective treatments requires innovative collaboration across disciplines and sectors to address complex healthcare challenges.
Breakthrough by William Pao review the drugs do workCreative innovation in drug development becomes a transformative force in medicine, driven by personal dedication and often serendipitous discoveries.
Berkeley startup wins government award to develop radiation and lead poisoning treatmentHOPO Therapeutics aims to develop drugs that selectively target and remove toxic metals from the body, posing a significant health threat.
How to transform scientific discoveries into better treatmentsTransforming scientific discoveries into effective treatments requires innovative collaboration across disciplines and sectors to address complex healthcare challenges.
Breakthrough by William Pao review the drugs do workCreative innovation in drug development becomes a transformative force in medicine, driven by personal dedication and often serendipitous discoveries.
Activist hedge fund Starboard met with Pfizer last week. Here's what went down.Starboard is advocating for increased accountability and improvements in Pfizer's operational and financial strategies. Smith highlights a poor return on investments.
Top Trends in the European Digital Health/AI Market | Data Matters Privacy BlogDigital health technologies are rapidly transforming drug development and healthcare delivery, with strong growth despite regulatory challenges.
The Next Potential Alzheimer's Drug Clears a Big HurdleDrug companies are making progress in Alzheimer's treatment with FDA panel's positive evaluation of Eli Lilly's donanemab.
Eli Lilly (LLY) Stock Price Prediction and Forecast 2025-2030Eli Lilly's stock has risen dramatically over recent years, showcasing strong market confidence and growth potential.Future projections for Eli Lilly's earnings and drug performance indicate significant growth opportunities despite recent safety concerns.
Eli Lilly (LLY) Stock Price Prediction and Forecast 2025-2030Eli Lilly's stock demonstrates a significant upward trajectory, driven by strategic expansions and innovative drug developments.
The Next Potential Alzheimer's Drug Clears a Big HurdleDrug companies are making progress in Alzheimer's treatment with FDA panel's positive evaluation of Eli Lilly's donanemab.
Eli Lilly (LLY) Stock Price Prediction and Forecast 2025-2030Eli Lilly's stock has risen dramatically over recent years, showcasing strong market confidence and growth potential.Future projections for Eli Lilly's earnings and drug performance indicate significant growth opportunities despite recent safety concerns.
Eli Lilly (LLY) Stock Price Prediction and Forecast 2025-2030Eli Lilly's stock demonstrates a significant upward trajectory, driven by strategic expansions and innovative drug developments.
How digital twins could save time, money, and lives in developing prescription drugsDigital twins in healthcare can transform drug development by simulating patient health, predicting outcomes, and optimizing treatment strategies.
The human touch, digital twins, and swiveling laptop screensHuman creativity remains irreplaceable in the workplace despite the rise of AI, emphasizing the need for early education in creativity.
How digital twins could save time, money, and lives in developing prescription drugsDigital twins in healthcare can transform drug development by simulating patient health, predicting outcomes, and optimizing treatment strategies.
The human touch, digital twins, and swiveling laptop screensHuman creativity remains irreplaceable in the workplace despite the rise of AI, emphasizing the need for early education in creativity.
How Machines Learned to Discover DrugsThe origins of medications in modern medicine pose existential questions, especially when treatments become ineffective.
Can Better Biotech Finally Replace Lab Animals?Itzy Morales Pantoja transitioned from animal testing to developing lab-grown models to advance neurodegeneration research and reduce reliance on animal studies.
A New Wave of Anti-Obesity Drugs Is on the WayTirzepatide's dual receptor activation may contribute to its efficacy in weight loss, while GIP's role is not fully understood yet.
Scientists turn white fat cells into calorie-burning beige fatTurning ordinary fat cells into calorie burners may lead to new weight-loss drug development.
A New Wave of Anti-Obesity Drugs Is on the WayTirzepatide's dual receptor activation may contribute to its efficacy in weight loss, while GIP's role is not fully understood yet.
Scientists turn white fat cells into calorie-burning beige fatTurning ordinary fat cells into calorie burners may lead to new weight-loss drug development.
Google DeepMind's latest medical breakthrough borrows a trick from AI image generatorsAI in medicine, like AlphaFold, showcases breakthroughs in predicting protein structures for disease research and drug development.
DeepMind's new AlphaFold 3 expands to DNA, RNA modelingAlphaFold 3 extends protein structure prediction to modeling interactions with DNA, RNA, and drugs, aiding in drug development.
Google DeepMind's latest medical breakthrough borrows a trick from AI image generatorsAI in medicine, like AlphaFold, showcases breakthroughs in predicting protein structures for disease research and drug development.
DeepMind's new AlphaFold 3 expands to DNA, RNA modelingAlphaFold 3 extends protein structure prediction to modeling interactions with DNA, RNA, and drugs, aiding in drug development.
New era of medicine breaks through against the most aggressive lung cancerNew drugs offer hope for small cell lung cancer treatment.
Feinberg Scientists to Lead Grant Studying Autism, Schizophrenia - News CenterNorthwestern Medicine secures $17 million grant to explore genetic causes of autism and schizophrenia for new drug development.
A disease-associated gene desert directs macrophage inflammation through ETS2 - NatureOnly 10% of drugs developed for autoimmune diseases are successful due to a lack of efficacy and poor understanding of disease mechanisms.
Alzheimer's scientist indicted for allegedly falsifying data in $16M schemeAn Alzheimer's researcher allegedly falsified data to secure $16 million in research funding for an Alzheimer's drug, raising doubts about the integrity of the research.The investigation revealed long-standing and egregious misconduct in data management by the researcher, leading to questions about the authenticity of the work.
Ketamine for depression: slow-release pills could make treatment more accessibleKetamine tablet could revolutionize depression treatment, offering a more convenient alternative to intravenous administration with reduced side effects.