The critical drivers of brain aging are now being understood through molecular studies, revealing both physical changes such as volume loss and biological factors like DNA damage.
Aging physically alters the brain through volume loss and changes in structural folds, causing it to literally shrink, impacting cognitive health significantly.
The brain's immune system deteriorates with age, contributing to decreasing cognitive health, while waste protein clearance becomes increasingly crucial for maintaining brain function.
With projections of 152 million individuals experiencing cognitive decline by 2050, identifying and addressing the factors that contribute to this deterioration has become more urgent.
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