#running-back-depth

#running-back-depth

Sanders dealt with a knee issue for a good portion of training camp but played in the first four games, picking up 117 yards on 20 carries. He did not play last week and was not able to finish practice on Wednesday. According to multiple sources, Sanders will undergo a chondral tissue graft surgery in which pieces of bone and cartilage were transplanted into the affected area to improve the joint function. Cornerback Trevon Diggs had the same surgery last January.

Los Angeles Chargers starting running back Omarion Hampton will be placed on injured reserve due to an ankle injury, coach Jim Harbaugh said Monday. By going on IR, Hampton will miss at least the next four games. The rookie sustained the injury in the Chargers' 27-10 loss to the Washington Commanders. It's the second major setback for the Chargers' running back depth chart this year.

Patriots running back Antonio Gibson is expected to miss the remainder of the season with a torn ACL after an MRI was performed on Monday, according to NFL Media's Ian Rapoport. Gibson left New England's 23-20 win against Buffalo after being hit in the knee during a kick return in the second quarter. Through five weeks of play, Gibson was the only player in the NFL with a kick return touchdown this season. He scored on a 90-yarder in Week 2 during the Patriots' win against the Dolphins.

It could be eight to 12 weeks,

After a one-yard run with 12:26 remaining in the third quarter, Cardinals running back James Conner was down due to injury. The cart had to come out for Conner, and that is rarely a good sign. Sources confirmed after Arizona's Week 3 loss that it was a season-ending injury for James Conner. Over his career, Conner has missed time due to injury. However, this is the most time he'll miss in a single season.