#pharmaceuticals
#pharmaceuticals

Swiss-based InVirtuoLabs raises 2.85M to accelerate drug development with AI - Silicon Canals

InVirtuoLabs secures â¬2.85M funding to reduce drug development time and costs, enhancing accessibility to treatments.

Paris-based B2B platform for pharma sector Faks raises 6M

Faks raises â¬6M to enhance its B2B platform, improving communication between pharmacies and pharmaceutical suppliers.

6 days ago

European startups

Finland's healthtech company CurifyLabs raises 6.7M

Scimplify raises $40M to help manufacturers access specialty chemicals | TechCrunch

Scimplify raises $40 million to expand its specialty chemicals platform and target new markets, especially in the U.S.

Venture

Swiss-based InVirtuoLabs raises 2.85M to accelerate drug development with AI - Silicon Canals

InVirtuoLabs secures â¬2.85M funding to reduce drug development time and costs, enhancing accessibility to treatments.

Paris-based B2B platform for pharma sector Faks raises 6M

Faks raises â¬6M to enhance its B2B platform, improving communication between pharmacies and pharmaceutical suppliers.

6 days ago

European startups

Finland's healthtech company CurifyLabs raises 6.7M

New weight-loss drugs like Mounjaro are hot right now. Eli Lilly's CEO explains why they're so expensive.

Weight-loss drugs are expensive due to the high development costs and the limited time to recoup investment before patents expire.

fromenglish.elpais.com

New anti-obesity drugs already outperform Ozempic

Simplistic approaches to obesity are largely ineffective long-term; modern treatments show promise in addressing the condition more effectively.

Design-Around Victory: Amgen's Self-Buffering Innovation Regeneron's Claims

The Federal Circuit affirmed Amgen's biosimilar, emphasizing its unique formulation and contrasting it with prior rulings against other manufacturers.

'Food is Medicine': The (Intentionally) Missing Prescription in Healthcare

Healthcare providers should embrace the 'Food is Medicine' movement as Americans demand nutrition guidance over pharmaceuticals.

UK news

Brexit a key factor in worst UK medicine shortages in four years, report says

Drug shortages in the UK are at a four-year high, largely attributed to Brexit-related supply chain issues.

fromRolling Stone

4 weeks ago

Republicans Want You to Pay More at the Pharmacy -- Or Die

Trump's proposed pharmaceutical tariffs threaten to drastically increase medication costs, affecting millions of Americans who rely on prescription drugs.

fromBusiness Insider

New weight-loss drugs like Mounjaro are hot right now. Eli Lilly's CEO explains why they're so expensive.

Weight-loss drugs are expensive due to the high development costs and the limited time to recoup investment before patents expire.

fromenglish.elpais.com

New anti-obesity drugs already outperform Ozempic

Simplistic approaches to obesity are largely ineffective long-term; modern treatments show promise in addressing the condition more effectively.

Design-Around Victory: Amgen's Self-Buffering Innovation Regeneron's Claims

The Federal Circuit affirmed Amgen's biosimilar, emphasizing its unique formulation and contrasting it with prior rulings against other manufacturers.

'Food is Medicine': The (Intentionally) Missing Prescription in Healthcare

Healthcare providers should embrace the 'Food is Medicine' movement as Americans demand nutrition guidance over pharmaceuticals.

UK news

Brexit a key factor in worst UK medicine shortages in four years, report says

Drug shortages in the UK are at a four-year high, largely attributed to Brexit-related supply chain issues.

fromRolling Stone

4 weeks ago

Republicans Want You to Pay More at the Pharmacy -- Or Die

Trump's proposed pharmaceutical tariffs threaten to drastically increase medication costs, affecting millions of Americans who rely on prescription drugs.

more#healthcare

#generic-drugs

fromIPWatchdog.com | Patents & Intellectual Property Law

Tax Victory for Generic Drug Companies: Federal Circuit Affirms ANDA Litigation Expenses are Deductible

Generic pharmaceutical companies can now deduct legal expenses from patent litigation as ordinary business expenses.

1 week ago

Intellectual property law

FTC Renews Campaign to Remove 'Junk' Inhaler and Device Patents from Orange Book Listings

fromIPWatchdog.com | Patents & Intellectual Property Law

Tax Victory for Generic Drug Companies: Federal Circuit Affirms ANDA Litigation Expenses are Deductible

Generic pharmaceutical companies can now deduct legal expenses from patent litigation as ordinary business expenses.

1 week ago

Intellectual property law

FTC Renews Campaign to Remove 'Junk' Inhaler and Device Patents from Orange Book Listings

more#generic-drugs

#ai

fromPsychology Today

AI Predicts Chemical Makeup From Photos

AI is transforming analytical chemistry by accurately predicting chemical compositions from images.

OMG science

Google plans to release new 'open' AI models for drug discovery | TechCrunch

Google is developing AI models for more efficient drug discovery called TxGemma.

fromBusiness Insider

This startup is using AI to give failed drugs a second chance. Check out the pitch deck it used to attract investors.

Ignota Labs leverages AI to revitalize failed drug candidates, increasing efficiency in the drug modification process and reducing costs significantly.

OpenAI and the FDA are reportedly discussing AI for drug evaluations | TechCrunch

OpenAI is collaborating with the FDA to explore AI tools for expediting drug evaluations.

fromHackernoon

7 months ago

Meet Chaindots, Sorintellis, and WISE.MARKET: HackerNoon Startups of The Week | HackerNoon

HackerNoon highlights three innovative startups excelling in software, healthcare, and supply chain management.

fromPsychology Today

AI Predicts Chemical Makeup From Photos

AI is transforming analytical chemistry by accurately predicting chemical compositions from images.

OMG science

Google plans to release new 'open' AI models for drug discovery | TechCrunch

Google is developing AI models for more efficient drug discovery called TxGemma.

fromBusiness Insider

This startup is using AI to give failed drugs a second chance. Check out the pitch deck it used to attract investors.

Ignota Labs leverages AI to revitalize failed drug candidates, increasing efficiency in the drug modification process and reducing costs significantly.

OpenAI and the FDA are reportedly discussing AI for drug evaluations | TechCrunch

OpenAI is collaborating with the FDA to explore AI tools for expediting drug evaluations.

fromHackernoon

7 months ago

Meet Chaindots, Sorintellis, and WISE.MARKET: HackerNoon Startups of The Week | HackerNoon

HackerNoon highlights three innovative startups excelling in software, healthcare, and supply chain management.

more#ai

#genetic-testing

Marketing tech

Bankrupt DNA testing firm 23andMe to be purchased for $256m

Regeneron Pharmaceuticals is acquiring 23andMe for $256 million amidst bankruptcy proceedings, focusing on customer data protection.

Marketing tech

Pharma giant Regeneron to buy 23andMe and its customers' data for $256M | TechCrunch

Marketing tech

Bankrupt DNA testing firm 23andMe to be purchased for $256m

Regeneron Pharmaceuticals is acquiring 23andMe for $256 million amidst bankruptcy proceedings, focusing on customer data protection.

Marketing tech

Pharma giant Regeneron to buy 23andMe and its customers' data for $256M | TechCrunch

Scientists Tweaked LSD's Molecular Structure and Created a Wild New Brain Drug

Researchers at UC Davis have modified LSD's structure to create a new compound, JRT, which aims to treat schizophrenia without causing hallucinations.

fromCbsnews

Novo Nordisk CEO Lars Jorgensen, who led company into weight loss drugs, to step down

Novo Nordisk's board and CEO Lars Fruergaard Jorgensen have agreed his departure is necessary due to recent market challenges and a significant decline in share price.

NYC startup

#weight-loss

Business intelligence

This Growth Stock Surged 63% in 2024. Here's Why 2025 Could Bring An Even Bigger Gain.

Eli Lilly stock has gained 63% in 2024, primarily due to the success of its Mounjaro weight-loss drug.

Public health

We know so little about taking weight-loss drugs without prescription is it really worth it? | Devi Sridhar

The popularity of GLP-1 drugs for weight loss is rising sharply, but concerns around safety and effectiveness remain largely unaddressed.

Zepbound trims more belly fat than Wegovy, study shows

Eli Lilly's Zepbound outperformed Novo Nordisk's Wegovy in a recent study, showing superior weight loss and waist circumference reduction.

Eli Lilly stock surges 15% after clinical trial of weight loss pill shows it works like Ozempic

Eli Lilly's orforglipron shows significant weight loss for Type 2 diabetes patients, potentially rivaling injectable medications.

Lilly's shares surged 15% following promising clinical trial results for orforglipron.

fromwww.scientificamerican.com

GLP-1 Weight-Loss Pills Are Challenging to Make. Here's Why

Oral GLP-1 drugs face significant hurdles, limiting their market presence compared to injectable forms.

fromFast Company

Growth hacking

Hims & Hers stock price soars after partnership with Novo Nordisk to offer weight-loss drug Wegovy

Business intelligence

This Growth Stock Surged 63% in 2024. Here's Why 2025 Could Bring An Even Bigger Gain.

Eli Lilly stock has gained 63% in 2024, primarily due to the success of its Mounjaro weight-loss drug.

Public health

We know so little about taking weight-loss drugs without prescription is it really worth it? | Devi Sridhar

The popularity of GLP-1 drugs for weight loss is rising sharply, but concerns around safety and effectiveness remain largely unaddressed.

Zepbound trims more belly fat than Wegovy, study shows

Eli Lilly's Zepbound outperformed Novo Nordisk's Wegovy in a recent study, showing superior weight loss and waist circumference reduction.

Eli Lilly stock surges 15% after clinical trial of weight loss pill shows it works like Ozempic

Eli Lilly's orforglipron shows significant weight loss for Type 2 diabetes patients, potentially rivaling injectable medications.

Lilly's shares surged 15% following promising clinical trial results for orforglipron.

fromwww.scientificamerican.com

GLP-1 Weight-Loss Pills Are Challenging to Make. Here's Why

Oral GLP-1 drugs face significant hurdles, limiting their market presence compared to injectable forms.

fromFast Company

Growth hacking

Hims & Hers stock price soars after partnership with Novo Nordisk to offer weight-loss drug Wegovy

Trump proposes U.S. auto tariffs could be 'in the neighbourhood' of 25% | CBC News

Trump's trade measures could impose 25% tariffs on auto, semiconductor, and pharmaceutical imports, threatening to disrupt international trade.

Trump floats 25% auto, drug, chip tariffs, upping trade threats

Trump plans to impose 25% tariffs on imports like automobiles, semiconductors, and pharmaceuticals, expanding his trade war by targeting multiple sectors.

US news

fromwww.npr.org

Pharmacists stockpile most common drugs on chance of targeted Trump tariffs

Tariffs on pharmaceuticals might increase prices and exacerbate drug shortages instead of bringing manufacturing back to the U.S.

US begins inquiry into pharmaceutical and chip imports in bid to impose tariffs

The Trump administration is investigating tariffs on pharmaceuticals and semiconductors to boost national security and domestic manufacturing.

Trump's Tariff Threat for Drug imports Poses Big Political Risks

Trump's tariff move on imported medicines could lead to higher drug prices and shortages.

fromTruthout

Tariffs on Pharmaceuticals May Be the Next Front in Trump's War on Public Health

Trump's proposed tariffs on pharmaceuticals could lead to higher costs and shortages of medications for U.S. patients.

fromwww.cbc.ca

Trump proposes U.S. auto tariffs could be 'in the neighbourhood' of 25% | CBC News

Trump's trade measures could impose 25% tariffs on auto, semiconductor, and pharmaceutical imports, threatening to disrupt international trade.

Trump floats 25% auto, drug, chip tariffs, upping trade threats

Trump plans to impose 25% tariffs on imports like automobiles, semiconductors, and pharmaceuticals, expanding his trade war by targeting multiple sectors.

US news

fromwww.npr.org

Pharmacists stockpile most common drugs on chance of targeted Trump tariffs

Tariffs on pharmaceuticals might increase prices and exacerbate drug shortages instead of bringing manufacturing back to the U.S.

US begins inquiry into pharmaceutical and chip imports in bid to impose tariffs

The Trump administration is investigating tariffs on pharmaceuticals and semiconductors to boost national security and domestic manufacturing.

Trump's Tariff Threat for Drug imports Poses Big Political Risks

Trump's tariff move on imported medicines could lead to higher drug prices and shortages.

fromTruthout

Tariffs on Pharmaceuticals May Be the Next Front in Trump's War on Public Health

Trump's proposed tariffs on pharmaceuticals could lead to higher costs and shortages of medications for U.S. patients.

Hims & Hers (HIMS) Down 21% - Is the GLP-1 Gravy Train Over?

Hims & Hers Health faces a significant stock drop due to the end of the Ozempic shortage, impacting its compounded drug market.

Healthcare

Republican Administration Maintains Exclusivity Stance in GLP-1 (Tirzepatide) Compounding Dispute

Public health

Critic of Covid boosters set to enact tough agenda as top US vaccines official

fromA Philosopher's Blog

philosophy

The FDA: Patients or Companies?

Health

Hims & Hers (HIMS) Down 21% - Is the GLP-1 Gravy Train Over?

Hims & Hers Health faces a significant stock drop due to the end of the Ozempic shortage, impacting its compounded drug market.

Republican Administration Maintains Exclusivity Stance in GLP-1 (Tirzepatide) Compounding Dispute

The ongoing demand for GLP-1s has resulted in a significant shortage and legal dispute regarding alternative compounding pharmacies.

Public health

Critic of Covid boosters set to enact tough agenda as top US vaccines official

Vinay Prasad's appointment as US vaccines official raises concerns about stricter regulatory scrutiny of pharmaceuticals and potential impacts on public health.

fromA Philosopher's Blog

philosophy

The FDA: Patients or Companies?

Trump signs executive order asking drugmakers to lower prescription drug costs within 30 days

Trump orders drug price cuts, threatening future limits if drugmakers do not comply.

fromMedCity News

US politics

Trump Strategy to Rein In Drug Prices Revives 'Most Favored Nation' Plan of His First Term - MedCity News

fromFast Company

Trump signs executive order asking drugmakers to lower prescription drug costs within 30 days

Trump orders drug price cuts, threatening future limits if drugmakers do not comply.

fromMedCity News

US politics

Trump Strategy to Rein In Drug Prices Revives 'Most Favored Nation' Plan of His First Term - MedCity News

more#drug-prices

#drug-pricing

fromNew York Magazine

fromIPWatchdog.com | Patents & Intellectual Property Law

US politics

5 Big Questions About Trump's Plan to Lower Drug Prices

Trump's executive order aims to reduce U.S. drug prices dramatically by aligning them with those in other countries.

Intellectual property law

Senate Judiciary Committee to Consider Bills Targeting Pharma Patents and Pricing

Congress is reviewing drug patent regulation legislation based on refuted data.

The Center for American Principles warns against bills influenced by misleading drug market data.

fromNew York Magazine

5 Big Questions About Trump's Plan to Lower Drug Prices

Trump's executive order aims to reduce U.S. drug prices dramatically by aligning them with those in other countries.

fromIPWatchdog.com | Patents & Intellectual Property Law

fromwww.independent.co.uk

Senate Judiciary Committee to Consider Bills Targeting Pharma Patents and Pricing

Congress is reviewing drug patent regulation legislation based on refuted data.

The Center for American Principles warns against bills influenced by misleading drug market data.

NYC startup

Pfizer (NYSE:PFE) Hasn't Been This Cheap in 13 Years. Time to Buy?

US news

European stocks rise as US and China agree to slash tariffs

NYC startup

Pfizer Inc. (NYSE: PFE) Price Prediction and Forecast 2025-2030 (April 2025)

Retirement

Eli Lilly (NYSE: LLY) Stock Price Prediction and Forecast 2025-2030 (May 2025)

Toronto startup

Billionaire Sold Broadcom And Bought This Stock That Could Soar 121%

fromwww.independent.co.uk

NYC startup

Pfizer (NYSE:PFE) Hasn't Been This Cheap in 13 Years. Time to Buy?

US news

European stocks rise as US and China agree to slash tariffs

NYC startup

Pfizer Inc. (NYSE: PFE) Price Prediction and Forecast 2025-2030 (April 2025)

Retirement

Eli Lilly (NYSE: LLY) Stock Price Prediction and Forecast 2025-2030 (May 2025)

Toronto startup

Billionaire Sold Broadcom And Bought This Stock That Could Soar 121%

more#stock-market

Big Pharma's Dirty Secret: How Prescription Drugs Are Starving Your Body of Essential Nutrients

Pharmaceuticals are depleting necessary nutrients, leading to health crises and increased dependency on medication.

Mainstream doctors often ignore the nutritional consequences of prescribing medications.

#gene-editing

NYC startup

Silicon Valley's gene-editor Synthego files for bankruptcy with plans tosell itself to lenders

fromTipRanks Financial

Marketing tech

Beam, Unity, Checkpoint, Inuvo, Ocular: Trending by Analysts - TipRanks.com

NYC startup

Silicon Valley's gene-editor Synthego files for bankruptcy with plans tosell itself to lenders

fromTipRanks Financial

Marketing tech

Beam, Unity, Checkpoint, Inuvo, Ocular: Trending by Analysts - TipRanks.com

more#gene-editing

#biotech

European startups

AstraZeneca to invest $2.5bn in drugs research and manfacturing in Beijing

fromBoston.com

NYC startup

Pharma company announces it will lay off 83 Boston-area employees

European startups

AstraZeneca to invest $2.5bn in drugs research and manfacturing in Beijing

fromBoston.com

NYC startup

Pharma company announces it will lay off 83 Boston-area employees

Millions of American kids have an ADHD diagnosis. Are they being treated effectively?

ADHD diagnoses have significantly risen, with concerns about the effectiveness and safety of medicating children.

Consumers can buy Zepbound direct from the drugmaker if they'll pay out of pocket

Eli Lilly's Zepbound reaches 100,000 direct buyers monthly, showing a shift towards online drug sales despite insurance coverage limitations.

fromFuturism

NYC startup

Eli Lilly's New Weight Loss Drug May Have the Worst Name in Pharmaceutical History

fromwww.npr.org

Consumers can buy Zepbound direct from the drugmaker if they'll pay out of pocket

Eli Lilly's Zepbound reaches 100,000 direct buyers monthly, showing a shift towards online drug sales despite insurance coverage limitations.

fromFuturism

NYC startup

Eli Lilly's New Weight Loss Drug May Have the Worst Name in Pharmaceutical History

more#obesity-treatment

#clinical-trials

UK news

NHS cancer patients denied life-saving drugs due to Brexit costs, report finds

Brexit is negatively impacting access to life-saving cancer drugs for UK patients.

fromNature

Cancer

Clinical trials by the numbers

Cancer is the second leading cause of death globally, requiring urgent advancements in diagnosis and treatment to keep pace with the rising incidence.

Emerging biopharmaceutical companies are increasingly dominating the oncology clinical trial landscape, reflecting their growing importance in cancer research.

UK news

NHS cancer patients denied life-saving drugs due to Brexit costs, report finds

Brexit is negatively impacting access to life-saving cancer drugs for UK patients.

Cancer

fromNature

Clinical trials by the numbers

Cancer is the second leading cause of death globally, requiring urgent advancements in diagnosis and treatment to keep pace with the rising incidence.

Emerging biopharmaceutical companies are increasingly dominating the oncology clinical trial landscape, reflecting their growing importance in cancer research.

Eli Lilly Sues 4 GLP-1 Telehealth Startups, Escalating War on Knockoff Drugs

FDA allowed compounding pharmacies a grace period to cease production post-drug shortage, but some continue to sell modified tirzepatide products.

Rare genetic disorder treated in womb for the first time

A child treated in the womb for spinal muscular atrophy shows no signs of the condition, marking a potential breakthrough in prenatal treatment.

New drug for Parkinson's shown to be effective in clinical trials: 'Very encouraged'

Tavapadon shows promise for Parkinson's by reducing symptoms more effectively and with fewer side effects than traditional treatments.

Medicine

fromNature

Rare genetic disorder treated in womb for the first time

A child treated in the womb for spinal muscular atrophy shows no signs of the condition, marking a potential breakthrough in prenatal treatment.

New drug for Parkinson's shown to be effective in clinical trials: 'Very encouraged'

Tavapadon shows promise for Parkinson's by reducing symptoms more effectively and with fewer side effects than traditional treatments.

more#neurology

#us-tariffs

Europe news

'Days of America being ripped off are over' - White House confirms Trump will go ahead with tariffs

Irish pharma exports to the US may face a significant decline due to impending tariffs.

UK politics

Ministers in active conversation' with UK drug firms over potential tariffs

Europe news

Countdown to Trump's tariffs: Tanaiste holding talks with European counterparts today

Europe news

'Days of America being ripped off are over' - White House confirms Trump will go ahead with tariffs

Irish pharma exports to the US may face a significant decline due to impending tariffs.

UK politics

Ministers in active conversation' with UK drug firms over potential tariffs

Europe news

Countdown to Trump's tariffs: Tanaiste holding talks with European counterparts today

Telemedicine and Prescription Drugs

Telemedicine is revolutionizing healthcare by enabling remote consultations and faster medication delivery, reshaping patient expectations and the pharma business.

Ancient kitchen secrets REVEALED: How garlic, ginger and green onions fight cancer and heart disease

Garlic, ginger, and green onions are potent natural ingredients with significant health benefits, validated by modern science.

Medicine

Combination of two cheap drugs could save lives after heart attack, study finds

Combining statins and ezetimibe could significantly reduce heart attack and stroke risks in patients.

#anime

SOMA, SF

Lazarus' Is a Dark and Kinetic Adventure

fromInverse

LA Clippers

Shinichiro Watanabe's New Anime Isn't Groundbreaking, But It's Still Cool As Hell

SOMA, SF

Lazarus' Is a Dark and Kinetic Adventure

fromInverse

LA Clippers

Shinichiro Watanabe's New Anime Isn't Groundbreaking, But It's Still Cool As Hell

more#anime

China, America and pay inject drama into AstraZeneca's AGM

AstraZeneca faces protests over executive pay while grappling with serious investigations in China, overshadowing its significant financial success due to strong treatment sales.

Europe news

#patent-law

fromIPWatchdog.com | Patents & Intellectual Property Law

fromIPWatchdog.com | Patents & Intellectual Property Law

Other Barks & Bites for Friday, March 7: Lashify Wins ITC Appeal on Economic Prong Analysis; CAFC Says Apple Did Not Violate Discovery Obligations at PTAB; and ParkerVision Files Reply Brief on Rule 36 Appeal at SCOTUS

Federal Circuit clarified discovery obligations for IPR petitioners.

Broadcom's AI chip demand positively impacted their Q1 results.

Novo Nordisk is leading in anti-obesity drug patents.

REPAIR Act aims to enhance automotive consumer rights.

Intellectual property law

Other Barks & Bites for Friday, March 28: House Passes Interagency R&D Bills; CAFC Affirms Induced Infringement Finding Against Mylan; and Several Drug Patent Bills Introduced into Congress

fromIPWatchdog.com | Patents & Intellectual Property Law

fromIPWatchdog.com | Patents & Intellectual Property Law

Other Barks & Bites for Friday, March 7: Lashify Wins ITC Appeal on Economic Prong Analysis; CAFC Says Apple Did Not Violate Discovery Obligations at PTAB; and ParkerVision Files Reply Brief on Rule 36 Appeal at SCOTUS

Federal Circuit clarified discovery obligations for IPR petitioners.

Broadcom's AI chip demand positively impacted their Q1 results.

Novo Nordisk is leading in anti-obesity drug patents.

REPAIR Act aims to enhance automotive consumer rights.

Intellectual property law

Other Barks & Bites for Friday, March 28: House Passes Interagency R&D Bills; CAFC Affirms Induced Infringement Finding Against Mylan; and Several Drug Patent Bills Introduced into Congress

more#patent-law

#investment

Drug giants in Ireland remain silent on future despite Donald Trump's aim to bring manufacturing back to the US

Ireland is a key player in global pharmaceutical production, employing 50,000 people and exporting â¬50bn annually.

fromIndependent

European startups

Investment tally shows big pharma pivot back to US already underway

Drug giants in Ireland remain silent on future despite Donald Trump's aim to bring manufacturing back to the US

Ireland is a key player in global pharmaceutical production, employing 50,000 people and exporting â¬50bn annually.

fromIndependent

European startups

Investment tally shows big pharma pivot back to US already underway

YC-backed ReactWise is applying AI to speed up drug manufacturing | TechCrunch

ReactWise uses AI to speed up drug manufacturing by optimizing chemical processes, significantly improving efficiency and accuracy.

NYC LGBT

On Good Footing After a Polo Tournament

Dr. Mercaitis celebrated his new job at Pfizer by participating in a polo tournament.

The Nasdaq is Cratering But REGN, BIIB and CSGP Are Up Big Today

Market uncertainty has intensified recession risks, impacting growth and spending.

Regeneron Pharmaceuticals shows positive trial results despite market downturn.

fromSlate Magazine