My husband has just been let go from his fourth job in five years. The first time it happened was during Covid when he was laid off, but it seemed to start a pattern.
After 40, stress physiology changes. Recovery slows. Hormonal responses linger longer. Sleep disruption compounds more quickly. Cognitive fatigue accumulates across weeks instead of days. Entrepreneurs, in particular, face chronic cognitive load: constant decision-making, emotional responsibility for teams, financial pressure (from investors, shareholders, and stakeholders), unpredictable stress cycles that follow you home to your family.
Loneliness and burnout-deeply interwined in the workplace-are hitting American workers (and companies) hard. In 2025, global healthcare firm Cigna found that over half of all employees surveyed felt lonely. Around 57% admitted to feeling unmotivated and stagnant, while two-thirds of full-time workers say they experience burnout on the job, according to a 2025 Gallup study. The financial toll is jaw-dropping. Harvard Business Review reports that loneliness costs U.S. companies up to $154 billion annually through lost productivity, increased burnout, and employees resigning.
